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. 2016 Sep;13(6):483-8.
doi: 10.11909/j.issn.1671-5411.2016.06.004.

Prognostic value of the ratio between prosthesis area and indexed annulus area measured by MultiSlice-CT for transcatheter aortic valve implantation procedures

Nicolas Debry  1 , Arnaud Sudre  1 , Ibrahim Elquodeimat  1 , Cédric Delhaye  1 , Guillaume Schurtz  1 , Antoine Bical  1 , Mohamad Koussa  1 , Khalil Fattouch  2 , Thomas Modine  1
Affiliations

Prognostic value of the ratio between prosthesis area and indexed annulus area measured by MultiSlice-CT for transcatheter aortic valve implantation procedures

Nicolas Debry et al. J Geriatr Cardiol. 2016 Sep.

Abstract

Background: Postprocedural aortic regurgitations following transcatheter aortic valve implantation (TAVI) procedures remain an issue. Benefit of oversizing strategies to prevent them isn't well established. We compared different level of oversizing in our cohort of consecutive patients to address if severe oversizing compared to normal sizing had an impact on post-procedural outcomes.

Methods: From January 2010 to August 2013, consecutive patients were referred for TAVI with preoperative Multislice-CT (MSCT) and the procedures were achieved using Edwards Sapien(®) or Corevalve devices(®). Retrospectively, according to pre-procedural MSCT and the valve size, patients were classified into three groups: normal, moderate and severe oversizing; depending on the ratio between the prosthesis area and the annulus area indexed and measured on MSCT. Main endpoint was mid-term mortality and secondary endpoints were the Valve Academic Research Consortium (VARC-2) endpoints.

Results: Two hundred and sixty eight patients had a MSCT and underwent TAVI procedure, with mainly Corevalve(®). While all-cause and cardiovascular mortality rates were similar in all groups, post-procedural new pacemaker (PM) implantation rate was significantly higher in the severe oversizing group (P = 0.03), while we observed more in-hospital congestive heart-failure (P = 0.02) in the normal sizing group. There was a trend toward more moderate to severe aortic regurgitation (AR) in the normal sizing group (P = 0.07).

Conclusions: Despite a higher rate of PM implantation, oversizing based on this ratio reduces aortic leak with lower rates of post-procedural complications and a similar mid-term survival.

Keywords: Aortic regurgitation; Aortic valve stenosis; Multislice-CT; Oversizing; Transcatheter aortic valve implantation.

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Figures

Figure 1.
Figure 1.. MSCT assessment of annular dimensions (area, short and long diameters).
MSCT: MultiSlice-CT.
Figure 2.
Figure 2.. (A) Long-term global mortality; (B) Long-term cardiovascular mortality.
See this image and copyright information in PMC

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