Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Sep;2(3):93-9.
doi: 10.1258/om.2009.090024. Epub 2009 Sep 1.

Sepsis in pregnancy and early goal-directed therapy

Affiliations
Review

Sepsis in pregnancy and early goal-directed therapy

Julie Joseph et al. Obstet Med. 2009 Sep.

Abstract

Sepsis is a major cause of serious morbidity and mortality in pregnant women and their babies. Conventional management has evolved over many years. Improved understanding of the underlying pathophysiology and randomized clinical trials have led to recommendations for the formalization and standardization of the management of severe sepsis in non-pregnant patients. Most of these recommendations are applicable to pregnancy. The Surviving Sepsis Campaign and Early Goal Directed Therapy have relevance to the care of pregnant women with serious infection and are reviewed here.

Keywords: early goal-directed therapy; pregnancy; sepsis.

PubMed Disclaimer

References

    1. Ronsmans C, Graham WJ. Lancet maternal survival series steering group. Maternal mortality: who, when, where, and why. Lancet 2006;368:1189–200 - PubMed
    1. Zentner D, du Plessis M, Brennecke S, et al. Deterioration in cardiac systolic and diastolic function late in normal human pregnancy. Clin Sci (Lond) 2009;116:599–606 - PubMed
    1. Niels le Souëf P, Walters BN. Neonatal listeriosis: a summer outbreak. Med J Aust 1981;22:188–91 - PubMed
    1. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20:864–74
    1. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250–6 - PubMed

LinkOut - more resources