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Review
. 2012 Sep;5(3):94-7.
doi: 10.1258/om.2012.110014. Epub 2012 May 29.

Pregnancy and multiple sclerosis

Affiliations
Review

Pregnancy and multiple sclerosis

Laura Airas et al. Obstet Med. 2012 Sep.

Abstract

The relapse rate of multiple sclerosis (MS) is typically reduced during late pregnancy but increases in the postpartum period. The reasons for the increased postpartum activity are not entirely clear, but factors such as the abrupt decrease in oestrogen levels immediately after the delivery and the loss of the immunosuppressive state of pregnancy are likely of importance. There is a general view that MS does not affect the course or outcome of pregnancy.

Keywords: immunosuppression; multiple sclerosis; pregnancy.

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References

    1. Coles A. Multiple sclerosis. Lancet 2008;372:1502–17 - PubMed
    1. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the ‘McDonald Criteria’. Ann Neurol 2005;58:840–6 - PubMed
    1. Orton SM, Herrera BM, Yee IM, et al. Sex ratio of multiple sclerosis in Canada: a longitudinal study. Lancet Neurol 2006;5:932–6 - PubMed
    1. Korn-Lubetzki I, Kahana E, Cooper G, Abramsky O. Activity of multiple sclerosis during pregnancy and puerperium. Ann Neurol 1984;16:229–31 - PubMed
    1. Millar JH, Allison RS, Cheeseman EA, Merrett JD. Pregnancy as a factor influencing relapse in disseminated sclerosis. Brain 1959;82:417–26 - PubMed

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