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. 2014 Jul 8;1(2):87-8.
doi: 10.4161/temp.29761. eCollection 2014 Jul-Sep.

Ischemia/reperfusion injury resistance in hibernators is more than an effect of reduced body temperature or winter season

Lori K Bogren  1 , Kelly L Drew  1
Affiliations

Ischemia/reperfusion injury resistance in hibernators is more than an effect of reduced body temperature or winter season

Lori K Bogren et al. Temperature (Austin). .

Abstract

Hibernating mammals are resistant to injury following cardiac arrest. The basis of this protection has been proposed to be due to their ability to lower body temperature or metabolic rate in a seasonally-dependent manner. However, recent studies have shown that neither reduced body temperature nor hibernation season are components this protection.

Keywords: body temperature; cardiac arrest; hemorrhagic shock; hibernation; hibernation season; ischemia/reperfusion; metabolism.

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Figures

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Figure 1.Ischemia/reperfusion injury resistance in arctic ground squirrels is not dependent on low body temperature or hibernation season but is due to metabolic stability defined as acid/base balance and the ability to switch between glucose and lipid energy sources to avoid lactate accumulation. (Photograph courtesy of Kim Turnball.)
See this image and copyright information in PMC

References

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