Experience with ifosfamide in paediatric tumours
- PMID: 2758568
- DOI: 10.1007/BF00253235
Experience with ifosfamide in paediatric tumours
Abstract
Ifosfamide, alone or in combination, is used in a variety of childhood tumours. Soft-tissue sarcomas are especially sensitive, with a 78% actuarial survival. Hyperaminoaciduria and a brief transient decrease in the plasma level of certain amino acids are the earliest signs of tubular toxicity.
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