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. 2016 Sep 1;63(5):726-8.
doi: 10.1016/j.molcel.2016.08.012.

Finding DNA Ends within a Haystack of Chromatin

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Finding DNA Ends within a Haystack of Chromatin

Ujjwal Banerjee et al. Mol Cell. .
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Abstract

Identifying DNA fragile sites is crucial to reveal hotspots of genomic rearrangements, yet their precise mapping has been a challenge. A new study in this issue of Molecular Cell (Canela et al., 2016) introduces a highly sensitive and accurate method to detect DNA breaks in vivo that can be adapted to various experimental and clinical settings.

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