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. 2016 Aug;161(4):587-92.
doi: 10.1007/s10517-016-3465-4. Epub 2016 Sep 3.

Development and Differentiation of Mesenchymal Bone Marrow Cells in Porous Permeable Titanium Nickelide Implants In Vitro and In Vivo

O V Kokorev  1 , V N Khodorenko  2 , A A Radkevich  2 , G Ts Dambaev  2 , V E Gunter  2
Affiliations

Development and Differentiation of Mesenchymal Bone Marrow Cells in Porous Permeable Titanium Nickelide Implants In Vitro and In Vivo

O V Kokorev et al. Bull Exp Biol Med. 2016 Aug.

Abstract

We studied the structure of porous permeable titanium nickelide used as the scaffold. In vitro population of the porous scaffold with multipotent mesenchymal stem bone marrow cells on days 7, 14, 21, and 28 was analyzed by scanning electron microscopy. Stage-by-stage histogenesis of the tissues formed from the bone marrow cells in the titanium nickelide scaffold in vivo is described in detail. Using mesenchymal stem cells, we demonstrated that porous permeable titanium nickelide scaffolds are unique incubators for cell cultures applicable for tissue engineering.

Keywords: biocompatibility; biomaterial; tissue bioengineering; titanium nickelide.

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