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Review
. 2016 Oct;25(4):721-33.
doi: 10.1016/j.soc.2016.05.005.

Management of Sarcoma Metastases to the Lung

Christopher S Digesu  1 , Ory Wiesel  1 , Ara A Vaporciyan  2 , Yolonda L Colson  3
Affiliations
Review

Management of Sarcoma Metastases to the Lung

Christopher S Digesu et al. Surg Oncol Clin N Am. 2016 Oct.

Abstract

For decades, surgical resection of pulmonary metastases has been performed; despite limited randomized data, surgery is increasingly accepted as an integral part in the management of metastatic disease. Long-term results indicate resection is potentially curative with significantly improved survival following complete resection. Recurrence, however, is not uncommon with many patients undergoing repeat resection. With advancing surgical technique and adjuvant therapies, patients with high or recurrent tumor burden are increasingly afforded disease control and potential cure. In this review, the prognostic characteristics of pulmonary metastases from sarcoma, preoperative evaluation, operative technique, long-term outcomes, and management of complex patients are highlighted.

Keywords: Prognostic factors; Pulmonary metastasectomy; SBRT; Sarcoma; Thoracic surgery; VATS.

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Figures

Figure 1
Figure 1
Kaplan Meier curve showing overall survival of patients PM from sarcoma stratified by DFI >12 months or J Surg Onc. 2015;112(1):103–106, with permission.
Figure 2
Figure 2
Extended resections with support of cardiopulmonary bypass in patients with sarcoma. A. Contrast chest CT of patient with leiomyosarcoma invading pulmonary arteries. B. Survival following extensive resection of sarcoma vs non-small cell lung cancer on cardiopulmonary bypass. From Wiebe K, Baraki H, Macchiarini P, et al. Extended pulmonary resection of advanced thoracic malignancies with support of cardiopulmonary bypass. Eur J Cardiothorac Surg. 2006. 29(4):571–7, with permission.
Figure 2
Figure 2
Extended resections with support of cardiopulmonary bypass in patients with sarcoma. A. Contrast chest CT of patient with leiomyosarcoma invading pulmonary arteries. B. Survival following extensive resection of sarcoma vs non-small cell lung cancer on cardiopulmonary bypass. From Wiebe K, Baraki H, Macchiarini P, et al. Extended pulmonary resection of advanced thoracic malignancies with support of cardiopulmonary bypass. Eur J Cardiothorac Surg. 2006. 29(4):571–7, with permission.
See this image and copyright information in PMC

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