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Review
. 2016 Nov;46(6):995-1013.
doi: 10.1016/j.cvsm.2016.06.001.

Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?

Larry D Cowgill  1 , David J Polzin  2 , Jonathan Elliott  3 , Mary B Nabity  4 , Gilad Segev  5 , Gregory F Grauer  6 , Scott Brown  7 , Cathy Langston  8 , Astrid M van Dongen  9
Affiliations
Review

Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?

Larry D Cowgill et al. Vet Clin North Am Small Anim Pract. 2016 Nov.

Abstract

International Renal Interest Society chronic kidney disease Stage 1 and acute kidney injury Grade I categorizations of kidney disease are often confused or ignored because patients are nonazotemic and generally asymptomatic. Recent evidence suggests these seemingly disparate conditions may be mechanistically linked and interrelated. Active kidney injury biomarkers have the potential to establish a new understanding for traditional views of chronic kidney disease, including its early identification and possible mediators of its progression, which, if validated, would establish a new and sophisticated paradigm for the understanding and approach to the diagnostic evaluation, and treatment of urinary disease in dogs and cats.

Keywords: IRIS AKI grade I; IRIS CKD stage 1; Kidney biomarkers; Progressive chronic kidney disease.

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