Taking stock of the occupational safety and health challenges of nanotechnology: 2000-2015
- PMID: 27594804
- PMCID: PMC5007006
- DOI: 10.1007/s11051-016-3459-1
Taking stock of the occupational safety and health challenges of nanotechnology: 2000-2015
Abstract
Engineered nanomaterials significantly entered commerce at the beginning of the 21st century. Concerns about serious potential health effects of nanomaterials were widespread. Now, approximately 15 years later, it is worthwhile to take stock of research and efforts to protect nanomaterial workers from potential risks of adverse health effects. This article provides and examines timelines for major functional areas (toxicology, metrology, exposure assessment, engineering controls and personal protective equipment, risk assessment, risk management, medical surveillance, and epidemiology) to identify significant contributions to worker safety and health. The occupational safety and health field has responded effectively to identify gaps in knowledge and practice, but further research is warranted and is described. There is now a greater, if imperfect, understanding of the mechanisms underlying nanoparticle toxicology, hazards to workers, and appropriate controls for nanomaterials, but unified analytical standards and exposure characterization methods are still lacking. The development of control-banding and similar strategies has compensated for incomplete data on exposure and risk, but it is unknown how widely such approaches are being adopted. Although the importance of epidemiologic studies and medical surveillance is recognized, implementation has been slowed by logistical issues. Responsible development of nanotechnology requires protection of workers at all stages of the technological life cycle. In each of the functional areas assessed, progress has been made, but more is required.
Keywords: Engineered nanomaterials; Epidemiology; History; Societal implications of nanotechnology; Toxicology.
Figures









Similar articles
-
OSHA Bloodborne Pathogen Standards.2023 Jul 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 Jul 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 34033323 Free Books & Documents.
-
Applying Translational Science Approaches to Protect Workers Exposed to Nanomaterials.Front Public Health. 2022 Jun 10;10:816578. doi: 10.3389/fpubh.2022.816578. eCollection 2022. Front Public Health. 2022. PMID: 35757639 Free PMC article. Review.
-
Occupational safety and health criteria for responsible development of nanotechnology.J Nanopart Res. 2014;16(1):2153. doi: 10.1007/s11051-013-2153-9. Epub 2013 Dec 7. J Nanopart Res. 2014. PMID: 24482607 Free PMC article.
-
The Minderoo-Monaco Commission on Plastics and Human Health.Ann Glob Health. 2023 Mar 21;89(1):23. doi: 10.5334/aogh.4056. eCollection 2023. Ann Glob Health. 2023. PMID: 36969097 Free PMC article. Review.
-
NIOSH field studies team assessment: Worker exposure to aerosolized metal oxide nanoparticles in a semiconductor fabrication facility.J Occup Environ Hyg. 2016 Nov;13(11):871-80. doi: 10.1080/15459624.2016.1183015. J Occup Environ Hyg. 2016. PMID: 27171535 Free PMC article.
Cited by
-
A Comparison of the Genotoxic Effects of Gold Nanoparticles Functionalized with Seven Different Ligands in Cultured Human Hepatocellular Carcinoma Cells.Nanomaterials (Basel). 2022 Mar 29;12(7):1126. doi: 10.3390/nano12071126. Nanomaterials (Basel). 2022. PMID: 35407243 Free PMC article.
-
The asbestos-carbon nanotube analogy: An update.Toxicol Appl Pharmacol. 2018 Dec 15;361:68-80. doi: 10.1016/j.taap.2018.06.027. Epub 2018 Jun 28. Toxicol Appl Pharmacol. 2018. PMID: 29960000 Free PMC article. Review.
-
Potential occupational hazards of additive manufacturing.J Occup Environ Hyg. 2019 May;16(5):321-328. doi: 10.1080/15459624.2019.1591627. Epub 2019 Mar 25. J Occup Environ Hyg. 2019. PMID: 30908118 Free PMC article. No abstract available.
-
Airborne LTA Nanozeolites Characterization during the Manufacturing Process and External Sources Interaction with the Workplace Background.Nanomaterials (Basel). 2022 Apr 24;12(9):1448. doi: 10.3390/nano12091448. Nanomaterials (Basel). 2022. PMID: 35564157 Free PMC article.
-
Comparison of Three Real-Time Measurement Methods for Airborne Ultrafine Particles in the Silicon Alloy Industry.Int J Environ Res Public Health. 2016 Sep 1;13(9):871. doi: 10.3390/ijerph13090871. Int J Environ Res Public Health. 2016. PMID: 27598180 Free PMC article.
References
-
- Amdur MO, Chen LC, Guty J, Lam HF, Miller PD. Speciation and pulmonary effects of acidic SOx formed on the surface of ultrafine zinc oxide aerosols. Atmos Environ (1967) 1988;22:557–560.
-
- Aschberger K, Christensen FM. Approaches for establishing human health no effect levels for engineered nanomaterials. J Phys. 2011;304:012078.
-
- BAM Bundestalt für material forschung and prüfung. http://www.nano-refmat.bam.de/en/category_10_nanobjects_nanoparticles_na....
-
- Bekker C, Kuijpers E, Brouwer DH, Vermeulen R, Fransman W. Occupational exposure to nano-objects and their agglomerates and aggregates across various life cycle stages. A Broad-Scale Exposure Study. Ann Occup Hyg. 2015;59:681–704. - PubMed
-
- Bergamaschi E. Occupational exposure to nanomaterials: present knowledge and future development. Nanotoxicology. 2009;3:194–201.
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources