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Case Reports
. 2016 Sep 1;4(1):17.
doi: 10.1186/s40364-016-0071-6. eCollection 2016.

Extramedullary hematopoiesis presented as cytopenia and massive paraspinal masses leading to cord compression in a patient with hereditary persistence of fetal hemoglobin

Tasleem Katchi  1 , Krishna Kolandaivel  1 , Pallavi Khattar  1 , Taliya Farooq  1 , Humayun Islam  1 , Delong Liu  1
Affiliations
Case Reports

Extramedullary hematopoiesis presented as cytopenia and massive paraspinal masses leading to cord compression in a patient with hereditary persistence of fetal hemoglobin

Tasleem Katchi et al. Biomark Res. .

Abstract

Background: Extramedullary hematopoeisis (EMH) can occur in various physiological and pathologic states. The spleen is the most common site of EMH.

Case presentation: We report a case with hereditary persistence of fetal hemoglobin with extramedullary hematopoiesis presented as cord compression and cytopenia secondary to multi-paraspinal masses.

Conclusion: Treatment can be a challenge. Relapse is a possibility.

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Figures

Fig. 1
Fig. 1
MRI study of the paraspinal masses. Representative images of the paraspinal masses were shown
Fig. 2
Fig. 2
Pathology of the thoracic paraspinal mass. The thoracic paraspinal mass was resected. H & E stain reviewed dense hematopoietic tissues. Immunostaining was positive for hemoglobin A (red cell) and CD61 (megakaryocytes)
See this image and copyright information in PMC

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