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Randomized Controlled Trial
. 2016 Sep 5;16(1):170.
doi: 10.1186/s12872-016-0356-6.

SMARTphone-based, early cardiac REHABilitation in patients with acute coronary syndromes [SMART-REHAB Trial]: a randomized controlled trial protocol

Matias B Yudi  1   2 , David J Clark  3   4 , David Tsang  5 , Michael Jelinek  4   6   7 , Katie Kalten  3 , Subodh Joshi  8 , Khoa Phan  8 , Arthur Nasis  9 , John Amerena  10 , Sandeep Arunothayaraj  6 , Chris Reid  11 , Omar Farouque  3   4
Affiliations
Randomized Controlled Trial

SMARTphone-based, early cardiac REHABilitation in patients with acute coronary syndromes [SMART-REHAB Trial]: a randomized controlled trial protocol

Matias B Yudi et al. BMC Cardiovasc Disord. .

Abstract

Background: There are well-documented treatment gaps in secondary prevention of coronary heart disease and no clear guidelines to assist early physical activity after acute coronary syndromes (ACS). Smartphone technology may provide an innovative platform to close these gaps. This paper describes the study design of a randomized controlled trial assessing whether a smartphone-based secondary prevention program can facilitate early physical activity and improve cardiovascular health in patients with ACS.

Methods: We have developed a multi-faceted, patient-centred smartphone-based secondary prevention program emphasizing early physical activity with a graduated walking program initiated on discharge from ACS admission. The program incorporates; physical activity tracking through the smartphone's accelerometer with interactive feedback and goal setting; a dynamic dashboard to review and optimize cardiovascular risk factors; educational messages delivered twice weekly; a photographic food diary; pharmacotherapy review; and support through a short message service. The primary endpoint of the trial is change in exercise capacity, as measured by the change in six-minute walk test distance at 8-weeks when compared to baseline. Secondary endpoints include improvements in cardiovascular risk factor status, psychological well-being and quality of life, medication adherence, uptake of cardiac rehabilitation and re-hospitalizations.

Discussion: This randomized controlled trial will use a smartphone-phone based secondary prevention program to emphasize early physical activity post-ACS. It will provide evidence regarding the feasibility and utility of this innovative platform in closing the treatment gaps in secondary prevention.

Trial registration: The trial was retrospectively registered in the Australian New Zealand Clinical Trials Registry (ANZCTR) on April 4, 2016. The registration number is ACTRN12616000426482 .

Keywords: Acute coronary syndromes; Cardiac rehabilitation; Secondary prevention; Smartphone application; mhealth.

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Figures

Fig. 1
Fig. 1
Randomized Control Trial Design and Flow
Fig. 2
Fig. 2
Smartphone application interface depicting interactive dashboard (a), cholesterol page (b), blood pressure progress chart (c), smoking education page (d), photographic food diary (e), activity tracking page (f), individualized messaging service (g) and medication page (h)
See this image and copyright information in PMC

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