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. 2016:2016:3614053.
doi: 10.1155/2016/3614053. Epub 2016 Aug 11.

Successful Treatment of Suspected Cannabinoid Hyperemesis Syndrome Using Haloperidol in the Outpatient Setting

Jennifer L Jones  1 , Karen E Abernathy  2
Affiliations

Successful Treatment of Suspected Cannabinoid Hyperemesis Syndrome Using Haloperidol in the Outpatient Setting

Jennifer L Jones et al. Case Rep Psychiatry. 2016.

Abstract

Chronic use of cannabis can result in a syndrome of hyperemesis characterized by cyclical vomiting without any other identifiable causes. Cannabinoid hyperemesis syndrome (CHS) is seldom responsive to traditional antiemetic therapies. Despite frequent nausea and vomiting, patients may be reluctant to discontinue use of cannabis. We report a case of severe, refractory CHS with complete resolution of nausea and vomiting after treatment with haloperidol in the outpatient setting. After review of the literature, we believe this is the first reported successful outpatient treatment of CHS and suggests a potential treatment for refractory patients.

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References

    1. Allen J. H., de Moore G. M., Heddle R., Twartz J. C. Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse. Gut. 2004;53(11):1566–1570. doi: 10.1136/gut.2003.036350. - DOI - PMC - PubMed
    1. Simonetto D. A., Oxentenko A. S., Herman M. L., Szostek J. H. Cannabinoid hyperemesis: a case series of 98 patients. Mayo Clinic Proceedings. 2012;87(2):114–119. doi: 10.1016/j.mayocp.2011.10.005. - DOI - PMC - PubMed
    1. Warner B., Cairns S., Stone A. A rare case of cannabis hyperemesis syndrome relieved by hot water bathing. Clinical Medicine. 2014;14(1):86–87. doi: 10.7861/clinmedicine.14-1-86. - DOI - PMC - PubMed
    1. Venkatesan T., Sengupta J., Lodhi A., et al. An Internet survey of marijuana and hot shower use in adults with cyclic vomiting syndrome (CVS) Experimental Brain Research. 2014;232(8):2563–2570. doi: 10.1007/s00221-014-3967-0. - DOI - PMC - PubMed
    1. Galli J. A., Sawaya R. A., Friedenberg F. K. Cannabinoid hyperemesis syndrome. Current Drug Abuse Reviews. 2011;4(4):241–249. doi: 10.2174/1874473711104040241. - DOI - PMC - PubMed

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