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Case Reports
. 2016 Jun;33(3):340-5.
doi: 10.4067/S0716-10182016000300016.

[Human herpes virus 6 infection in an inmunocompetent patient with carbamazepine-induced DRESS syndrome]

[Article in Spanish]
Sergio Álvarez  1 , Ignacio Delama  2 , Lucas Navajas-Galimany  1 , Gonzalo Eymin  3 , M Elena Ceballos  2 , Romina Andino-Navarrete  4
Affiliations
Case Reports

[Human herpes virus 6 infection in an inmunocompetent patient with carbamazepine-induced DRESS syndrome]

[Article in Spanish]
Sergio Álvarez et al. Rev Chilena Infectol. 2016 Jun.

Abstract

DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) is an adverse life-threatening drug reaction characterized by a polymorphous rash associated with fever, lymphadenopathy and multiorgan involvement with eosinophilia. We present the case of an immunocompetent man with DRESS syndrome secondary to carbamazepine, that developed concomitantly meningoencephalitis caused by human herpes virus 6 (HHV-6), and a review of literature. The pathogenic role of HHV-6 in DRESS syndrome remains controversial. Given the diagnostic and possibly prognostic significance of HHV-6, the screening seems to be a good measure to use in the clinical management of these patients.

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