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. 2016 Jul;469(1):244-6.
doi: 10.1134/S1607672916040037. Epub 2016 Sep 7.

Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds

A V Baron  1   2 , N V Osipov  3 , S V Yashchenko  3 , Yu A Kokotukha  3 , I J Baron  4 , A P Puzyr  5 , I A Olkhovskiy  6   7 , V S Bondar  5
Affiliations

Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds

A V Baron et al. Dokl Biochem Biophys. 2016 Jul.

Abstract

Adsorption of viral particles from the blood plasma of patients with viral hepatitis B and C on modified nanodiamonds (MNDs) was shown in the in vitro experiments. PCR method showed the treatment of plasma with MNDs leads to a decrease in the viral load by 2-3 orders of magnitude or more in both cases studied. These results make it possible to predict the applicability of MNDs for the development of new technologies of hemodialysis and plasmapheresis for binding and removal of viral particles from the blood of infected patients.

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References

    1. Dokl Biochem Biophys. 2014;457:158-9 - PubMed

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