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Editorial
. 2016 Nov 1;34(31):3717-3718.
doi: 10.1200/JCO.2016.69.0040.

Theory Meets Practice for Immune Checkpoint Blockade in Small-Cell Lung Cancer

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Editorial

Theory Meets Practice for Immune Checkpoint Blockade in Small-Cell Lung Cancer

Jonathan W Riess et al. J Clin Oncol. .
No abstract available

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References

    1. Riess JW, Lara PN., Jr Left behind? Drug discovery in extensive-stage small-cell lung cancer. Clin Lung Cancer. 2014;15:93–95. - PMC - PubMed
    1. Govindan R, Page N, Morgensztern D, et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol. 2006;24:4539–4544. - PubMed
    1. McGranahan N, Furness AJ, Rosenthal R, et al. Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade. Science. 2016;351:1463–1469. - PMC - PubMed
    1. Rizvi NA, Hellmann MD, Snyder A, et al. Cancer immunology: Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science. 2015;348:124–128. - PMC - PubMed
    1. Peifer M, Fernández-Cuesta L, Sos ML, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet. 2012;44:1104–1110. - PMC - PubMed

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