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Case Reports
. 2016 May-Aug;20(2):300-3.
doi: 10.4103/0973-029X.185915.

White sponge nevus: Report of three cases in a single family

Ngairangbam Sanjeeta  1 , D B Nandini  1 , Takhellambam Premlata  2 , Sumita Banerjee  1
Affiliations
Case Reports

White sponge nevus: Report of three cases in a single family

Ngairangbam Sanjeeta et al. J Oral Maxillofac Pathol. 2016 May-Aug.

Abstract

White sponge nevus (WSN) is an interesting hereditary oral mucosal disorder that commonly manifests as bilaterally symmetrical, thickened white, corrugated or velvety, diffuse plaques that predominantly affects the buccal mucosa. The lesions may develop at birth or later in childhood or adolescence. Because it is asymptomatic and benign, WSN requires no treatment. Recognition of this disorder is important due to its potential confusion with other lesions that may be found in the oral cavity. Emphasis should be given to the early and correct diagnosis of this disorder to avoid unnecessary treatment. This report presents three affected members of a single family.

Keywords: CK 13; CK 4; Cannon disease; genodermatosis; spongiosis; white plaque; white sponge nevus.

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Figures

Figure 1
Figure 1
Clinical image showing diffuse, soft and thickened white plaque with corrugated surface on left buccal mucosa
Figure 2
Figure 2
Clinical image showing lesions on the dorsal surface tongue, right buccal mucosa and parts of the palatal mucosa
Figure 3
Figure 3
Clinical image showing lesions on right buccal mucosa of the father
Figure 4
Figure 4
Clinical image showing scattered lesions on right buccal mucosa of the brother
Figure 5
Figure 5
Histopathological picture showing hyperplastic keratinized squamous epithelium with prominent hyperparakeratosis, marked acanthosis and spongiosis (H&E stain, ×50)
Figure 6
Figure 6
Histopathological picture showing cells with clearing of the cytoplasm and perinuclear eosinophilic condensation (H&E stain, ×200)
Figure 7
Figure 7
High power view of the section shows cells with clearing of the cytoplasm and perinuclear eosinophilic condensation (H&E stain, ×400)
See this image and copyright information in PMC

References

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