Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2016 Sep;95(36):e4613.
doi: 10.1097/MD.0000000000004613.

Evaluation of Ex-PRESS implantation combined with phacoemulsification in primary angle-closure glaucoma

Bing Liu  1 , Da-Dong Guo, Xiu-Juan Du, Chen-Yang Cong, Xiao-Hua Ma
Affiliations
Observational Study

Evaluation of Ex-PRESS implantation combined with phacoemulsification in primary angle-closure glaucoma

Bing Liu et al. Medicine (Baltimore). 2016 Sep.

Abstract

To evaluate the safety and efficacy of Ex-PRESS (R50) implantation combined with phacoemulsification in primary angle-closure glaucoma (PACG) patients with cataract.Twenty-four eyes of 24 patients with unregulated PACG underwent combined cataract and glaucoma surgery. After phacoemulsification and intraocular lens implantation, the Ex-PRESS (R-50) was inserted into the anterior chamber under a scleral flap. The intraocular pressure (IOP), best corrected visual acuity (BCVA), number of medications, and complications were recorded preoperatively as well as postoperatively on day 7 and at 1, 3, 6, and 12 months.The mean follow-up was 16.4 ± 2.5 months (range 14-21 months) and the mean age of the patients was 64.7 ± 6.8 years (range 56-78 years). The mean IOP was 20.4 ± 5.4 mm Hg preoperatively and decreased to 10.2 ± 2.8, 13.1 ± 2.7, 14.9 ± 4.1, 14.3 ± 3.9, and 14.0 ± 3.6 mm Hg on day 7 and at 1, 3, 6, and 12 months after surgery (all P < 0.005). At 12 months, the mean BCVA was 0.62 ± 0.33 and the number of medications was 0.3 ± 0.6. Most of complications were resolved spontaneously and conservatively.The Ex-PRESS implantation combined with phacoemulsification cataract extraction is safe and effective for reducing IOP and antiglaucoma medications in PACG patients with cataract.

PubMed Disclaimer

Conflict of interest statement

The authors have no funding and conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Mean IOP before surgery and at each follow-up period. The bars represent the standard deviation. d = day, IOP = intraocular pressure, m = month, Pre = preoperative IOP.
Figure 2
Figure 2
Mean number of glaucoma medications before surgery and at each follow-up period. The bars represent the standard deviation. d = day, m = month, Pre = preoperative number of antiglaucoma medications.
Figure 3
Figure 3
Kaplan–Meier survival analysis.
See this image and copyright information in PMC

References

    1. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006; 90:262–267. - PMC - PubMed
    1. Mosaed S, Minckler DS. Aqueous shunts in the treatment of glaucoma. Expert Rev Med Devices 2010; 7:661–666. - PubMed
    1. Borisuth NS, Phillips B, Krupin T. The risk profile of glaucoma filtration surgery. Curr Opin Ophthalmol 1999; 10:112–116. - PubMed
    1. Gedde SJ, Herndon LW, Brandt JD, et al. Surgical complications in the tube versus trabeculectomy study during the first year of follow-up. Am J Ophthalmol 2007; 143:23–31. - PubMed
    1. Wang W, Zhou M, Huang W, et al. Ex-PRESS implantation versus trabeculectomy in uncontrolled glaucoma: a meta-analysis. PLoS ONE 2013; 8:e63591. - PMC - PubMed

Publication types