Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2016 Jul 28;22(28):6527-38.
doi: 10.3748/wjg.v22.i28.6527.

Trends and predictions for gastric cancer mortality in Brazil

Angela Carolina Brandão de Souza Giusti  1 , Pétala Tuani Candido de Oliveira Salvador  1 , Juliano Dos Santos  1 , Karina Cardoso Meira  1 , Amanda Rodrigues Camacho  1 , Raphael Mendonça Guimarães  1 , Dyego L B Souza  1
Affiliations
Observational Study

Trends and predictions for gastric cancer mortality in Brazil

Angela Carolina Brandão de Souza Giusti et al. World J Gastroenterol. .

Abstract

Aim: To analyze the effect of age-period and birth cohort on gastric cancer mortality, in Brazil and across its five geographic regions, by sex, in the population over 20 years of age, as well as make projections for the period 2010-2029.

Methods: An ecological study is presented herein, which distributed gastric cancer-related deaths in Brazil and its geographic regions. The effects of age-period and birth cohort were calculated by the Poisson regression model and projections were made with the age-period-cohort model in the statistical program R.

Results: Progressive reduction of mortality rates was observed in the 1980's, and then higher and lower mortality rates were verified in the 2000's, for both sexes, in Brazil and for the South, Southeast and Midwest regions. A progressive decrease in mortality rates was observed for the Northeast (both sexes) and North (men only) regions within the period 1995-1999, followed by rising rates.

Conclusion: Regional differences were demonstrated in the mortality rates for gastric cancer in Brazil, and the least developed regions of the country will present increases in projected mortality rates.

Keywords: Brazil; Gastric neoplasms; Mortality; Projections.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Mortality from gastric cancer according to sex and geographical regions, in Brazil, 1980 to 2009.
Figure 2
Figure 2
Results of the Age-period-cohort model, adjusted for gastric cancer mortality, according to to sex and geographical regions, in Brazil, 1980 to 2009.
Figure 3
Figure 3
World age-standardized rates, changes in numbers of deaths relative change due to risk and changed population, between 2005-2009 (observed) and 2025–2029 (predicted) of gastric cancer mortality in Brazil. ASW: Age-standardized rates; Pop: Population.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:E359–E386. - PubMed
    1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893–2917. - PubMed
    1. Compare D, Rocco A, Nardone G. Risk factors in gastric cancer. Eur Rev Med Pharmacol Sci. 2010;14:302–308. - PubMed
    1. Matsuzaka M, Fukuda S, Takahashi I, Shimaya S, Oyama T, Yaegaki M, Shimoyama T, Sakamoto J, Nakaji S, Umeda T. The decreasing burden of gastric cancer in Japan. Tohoku J Exp Med. 2007;212:207–219. - PubMed
    1. Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol. 2006;12:354–362. - PMC - PubMed

Publication types