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Review
. 2017 Feb;27(2):136-140.
doi: 10.1016/j.tcm.2016.07.006. Epub 2016 Aug 3.

Cardiovascular disease in patients with rheumatoid arthritis

Katherine P Liao  1
Affiliations
Review

Cardiovascular disease in patients with rheumatoid arthritis

Katherine P Liao. Trends Cardiovasc Med. 2017 Feb.

Abstract

The risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) is 1.5-2-fold higher than age- and sex-matched individuals from the general population. This excess risk is attributed to the systemic chronic inflammation which is a hallmark of RA. Challenges to optimizing CV risk management in RA include the need for improved methods to predict CV risk, and defining the target risk factor(s) to reduce CV risk. Lessons learned from RA studies can also inform CV risk prevention in the general population, where inflammation also has an important role in the pathogenesis of atherosclerosis.

Keywords: Cardiovascular disease; Inflammation; Lipids; Lipoproteins; Rheumatoid arthritis.

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Figures

Figure 1
Figure 1
The mean hsCRP from a general population cohort*, hsCRP cut-off values for CV risk estimation in the general population, compared to the mean hsCRP from a typical RA cohort**. [*National Health and Nutrition Examination Survey (NHANES), **Brigham Rheumatoid Arthritis Sequential Study (BRASS)]
See this image and copyright information in PMC

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