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Comment
. 2016 Nov;24(11):850-852.
doi: 10.1016/j.tim.2016.08.007. Epub 2016 Sep 7.

Biomimetic Salmonella: A Next-Generation Therapeutic Vector?

Sebastian Felgner  1 , Dino Kocijancic  2 , Vinay Pawar  3 , Siegfried Weiss  3
Affiliations
Comment

Biomimetic Salmonella: A Next-Generation Therapeutic Vector?

Sebastian Felgner et al. Trends Microbiol. 2016 Nov.

Abstract

Designing bacterial vectors for cancer therapy represents a major challenge. Recent studies have explored novel strategies to balance benefit and safety. A study by Mercado-Lubo et al. has developed a next-generation concept combining bacterial properties with nanoparticles, demonstrating efficacy in combination with chemotherapeutics.

Keywords: Salmonella Typhimurium; Salmonella-mediated tumor therapy; SipA; nanoparticles.

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