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. 2016 May 10;26(3):e3621.
doi: 10.5812/ijp.3621. eCollection 2016 Jun.

Follow-Up Results of Device Occlusion of Patent Ductus Arteriosus

Hamid Amoozgar  1 , Sara Salehi  1 , Pouya Farhadi  2 , Mohammad Reza Edraki  1 , Mohammad Borzoee  1 , Gholamhossein Ajami  1 , Sirous Cheriki  1 , Hamid Mohammadi  1
Affiliations

Follow-Up Results of Device Occlusion of Patent Ductus Arteriosus

Hamid Amoozgar et al. Iran J Pediatr. .

Abstract

Background: Transcatheter patent ductus arteriosus (PDA) closure is an established procedure.

Objectives: The aim of the study was to assess midterm follow up of the Nit-Occlud coil and the amplatzer ductal occluder (ADO) closure of PDA.

Patients and methods: In this cohort study, we collected the longitudinal data of patients who underwent percutaneous closure using coil or ADO from November 2005 to November 2013. A total of 404 patients with PDA closure by devices were included during the study period. Coil occlusion was performed in 220 patients and 184 patients underwent catheterization using ADO. Follow-up evaluations were performed with echocardiography at two weeks, two months, six months, and during the study period (in average 4.8 ± 3.8 years).

Results: The patients' mean age was 24 months (range: 1 - 312). The catheterization was successful in 393 (97.2%) patients and unsuccessful in 11 (2.7%). Immediate complete occlusion was seen in 290 (73.7 %) patients. The occlusion rates at two weeks, two months, six months, and during the study period were 73.7%, 84%, 93.6%, 98.7%, and 99.5%, respectively. Complications occurred in 23 (5.8%) patients during or immediately after the catheterization, and device embolization with 2.7% was the most common complication. Most complications occurred in a patient with pulmonary hypertension who was less than one year old and was undergoing the first year of experience with devices.

Conclusions: Our findings showed that transcatheter occlusion of the PDA is an effective and safe intervention by coil or Amplatzer with excellent early and one-year outcomes. Pulmonary hypertension, age of less than 12 months and experience of less than one year may increase the complications of device closure.

Keywords: Amplatzer Ductal Occlude; Coil Occlusion; Patent Ductus Arteriosus; Transcatheter Occlusion; Treatment Outcome.

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