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Review
. 2016 Jun;5(2):98-104.
doi: 10.1055/s-0036-1579766. Epub 2016 Mar 9.

Neurofibromatosis: A Review of NF1, NF2, and Schwannomatosis

Jesse Lee Kresak  1 , Meggen Walsh  1
Affiliations
Review

Neurofibromatosis: A Review of NF1, NF2, and Schwannomatosis

Jesse Lee Kresak et al. J Pediatr Genet. 2016 Jun.

Abstract

The neurofibromatoses are a heterogeneous group of hereditary cancer syndromes that lead to tumors of the central and peripheral nervous systems, as well as other organ systems. By far the most common form is neurofibromatosis 1 (96%), followed by neurofibromatosis 2 (3%), and a more recently recognized, lesser known form, schwannomatosis. The diagnostic criteria, pathogenesis, molecular considerations, and clinical manifestations are discussed in this review article.

Keywords: NF1; NF2; neurofibromatosis; schwannomatosis; von Recklinghausen disease.

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