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. 2016 Sep 7;5(9):79.
doi: 10.3390/jcm5090079.

Adherence to Glaucoma Medications Over 12 Months in Two US Community Pharmacy Chains

Michael Feehan  1   2 , Mark A Munger  3 , Daniel K Cooper  4 , Kyle T Hess  5 , Richard Durante  6 , Gregory J Jones  7 , Jaime Montuoro  8 , Margaux A Morrison  9 , Daniel Clegg  10 , Alan S Crandall  11 , Margaret M DeAngelis  12
Affiliations

Adherence to Glaucoma Medications Over 12 Months in Two US Community Pharmacy Chains

Michael Feehan et al. J Clin Med. .

Abstract

This study determined the degree of adherence to medications for glaucoma among patients refilling prescriptions in community pharmacies.

Methods: Data abstracted from the dispensing records for 3615 adult patients (18 years or older, predominantly over 45) receiving glaucoma medications from two retail pharmacy chains (64 stores in total) were analyzed. From a 24-month historic data capture period, the 12-month levels of adherence were determined using standard metrics, the proportion of days covered (PDC) and the medication possession ratio (MPR). The overall 12-month mean PDC was only 57%, and the mean MPR was 71%. Using a criterion by which 80% coverage was considered satisfactory adherence, only 30% had satisfactory overall 12-month PDC coverage, and only 37% had satisfactory overall 12-month MPR coverage. Refill adherence increased with age and was highest in the 65-and-older age group (p < 0.001). Differential adherence was found across medication classes, with the highest satisfactory coverage seen for those taking alpha2-adrenergic agonists (PDC = 36.0%; MPR = 47.6%) down to those taking direct cholinergic agonists (PDC = 25.0%; MPR = 31.2%) and combination products (PDC = 22.7%; MPR = 31.0%). Adherence to glaucoma medications in the community setting, as measured by pharmacy refill data, is very poor and represents a critical target for intervention. Community pharmacists are well positioned to monitor and reinforce adherence in this population.

Keywords: adherence; glaucoma; pharmacy.

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Conflict of interest statement

The authors declare no conflict of interest. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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