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Case Reports
. 2016 Nov 3;128(18):2270-2272.
doi: 10.1182/blood-2016-08-732610. Epub 2016 Sep 12.

Acute myeloid leukemia with TP53 germ line mutations

Armin Zebisch  1 , Ridhima Lal  1 , Marian Müller  1 , Karin Lind  1 , Karl Kashofer  2 , Michael Girschikofsky  3 , David Fuchs  4 , Albert Wölfler  1 , Jochen B Geigl  5 , Heinz Sill  1
Affiliations
Case Reports

Acute myeloid leukemia with TP53 germ line mutations

Armin Zebisch et al. Blood. .
No abstract available

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Figures

Figure 1
Figure 1
An LFS pedigree showing for the first time familial clustering of AML. The index patient developed tAML (II:4) following cytotoxic treatment of diverse antecedent malignancies, and the index patient’s father (I:2) developed sAML following myelodysplasia. Filled symbols, subjects with malignancies; asterisk denotes a TP53 c.467G>C, p.R156P germ line mutation carrier; the “minus” denotes a wild-type TP53 germ line status. Numbers in brackets indicate age at diagnosis in years. BC, breast cancer; CML, chronic myeloid leukemia; CRC, colorectal cancer; PNET, primitive neuroectodermal tumor; TC, thyroid carcinoma.
See this image and copyright information in PMC

References

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