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. 2016 Sep 2:10:1713-7.
doi: 10.2147/OPTH.S116859. eCollection 2016.

Correlation between short-term and long-term intraocular pressure fluctuation in glaucoma patients

Naoki Tojo  1 , Shinya Abe  1 , Mari Miyakoshi  1 , Atsushi Hayashi  1
Affiliations

Correlation between short-term and long-term intraocular pressure fluctuation in glaucoma patients

Naoki Tojo et al. Clin Ophthalmol. .

Abstract

Purpose: We investigated correlations between short-term and long-term intraocular pressure (IOP) fluctuations.

Methods: We examined 50 eyes of glaucoma patients who were followed for >2 years. We measured short-term IOP fluctuation using a Triggerfish(®) contact lens sensor (CLS). The short-term IOP fluctuation (mVeq) was defined as the difference between the maximum value and the minimum value measured during the 24-hour course with CLS. The long-term IOP fluctuation was defined by four parameters: 1) the mean IOP (mmHg) determined during follow-up; 2) the IOP difference, which was defined as the difference between the maximum IOP and the minimum IOP; 3) the standard deviation of IOP; and 4) the peak IOP, which was defined as the maximum IOP. Correlations between these parameters and the short-term IOP fluctuation were examined.

Results: The mean follow-up period was 5.4 years. The average IOP was 15.0±4.0 mmHg. The range of short-term IOP fluctuation identified with CLS was significantly correlated with all the four long-term IOP fluctuation parameters.

Conclusion: Short-term IOP fluctuations were found to be associated with long-term IOP fluctuations. Examination of 24-hour IOP fluctuations with the CLS might be useful for predicting the long-term IOP fluctuation.

Keywords: Triggerfish®; contact lens sensor; fluctuation; intraocular pressure.

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Figures

Figure 1
Figure 1
The correlation between short-term and long-term IOP fluctuation parameters. Notes: Correlation between (A) mean IOP and IOP fluctuation with CLS, (B) standard deviation of IOP and IOP fluctuation with CLS, (C) peak IOP and IOP fluctuation with CLS, and (D) IOP difference and IOP fluctuation with CLS. Abbreviations: IOP, intraocular pressure; CLS, contact lens sensor.
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