Glucose Metabolism: A Sweet Relief of Alzheimer's Disease
- PMID: 27623263
- DOI: 10.1016/j.cub.2016.07.060
Glucose Metabolism: A Sweet Relief of Alzheimer's Disease
Abstract
Patients and individuals at risk for Alzheimer's disease show reduced glucose metabolism in the brain. A new study takes advantage of a fly model of Alzheimer's disease to demonstrate that enhancing glucose uptake in neurons has strong neuroprotective effects involving improved proteostasis.
Copyright © 2016 Elsevier Ltd. All rights reserved.
Comment on
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Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila.Curr Biol. 2016 Sep 12;26(17):2291-300. doi: 10.1016/j.cub.2016.07.017. Epub 2016 Aug 11. Curr Biol. 2016. PMID: 27524482 Free PMC article.
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