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Comment
. 2016 Sep 13;316(10):1106-7.
doi: 10.1001/jama.2016.11044.

Colchicine and Prevention of Cardiovascular Events

Lars G Hemkens  1 , Hannah Ewald  1 , Matthias Briel  2
Affiliations
Comment

Colchicine and Prevention of Cardiovascular Events

Lars G Hemkens et al. JAMA. .

Abstract

Clinical question: Is continuous long-term treatment with colchicine associated with lower rates of all-cause mortality and myocardial infarction and higher rates of adverse events?

Bottom line: Continuous long-term treatment with colchicine may be associated with lower rates of myocardial infarction, but may be associated with higher rates of gastrointestinal adverse events.

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Comment on

  • Colchicine for prevention of cardiovascular events.
    Hemkens LG, Ewald H, Gloy VL, Arpagaus A, Olu KK, Nidorf M, Glinz D, Nordmann AJ, Briel M. Hemkens LG, et al. Cochrane Database Syst Rev. 2016 Jan 27;2016(1):CD011047. doi: 10.1002/14651858.CD011047.pub2. Cochrane Database Syst Rev. 2016. PMID: 26816301 Free PMC article.