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Case Reports
. 2016 Aug 5;8(8):e725.
doi: 10.7759/cureus.725.

Duodenal Amyloidosis Masquerading as Iron Deficiency Anemia

Faisal Inayat  1 , Abu Hurairah  2
Affiliations
Case Reports

Duodenal Amyloidosis Masquerading as Iron Deficiency Anemia

Faisal Inayat et al. Cureus. .

Abstract

The present study is a unique illustration of duodenal amyloidosis initially manifesting with iron deficiency anemia. It underscores the importance of clinical suspicion of amyloidosis while performing upper gastrointestinal endoscopy with a biopsy to establish the definite diagnosis in patients with unexplained iron deficiency anemia.

Keywords: gastrointestinal amyloidosis; iron deficiency anemia.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Duodenal Biopsy
Photomicrograph reveals mucosal biopsy showing glassy pink material in the lamina propria.
Figure 2
Figure 2. Intact Mucosal Biopsy of the Duodenum
Photomicrograph reveals a glassy pink material in the lamina propria with mild to moderate chronic inflammatory infiltrate predominantly composed of lymphocytes.
Figure 3
Figure 3. Duodenal Biopsy Specimen Stained with Congo Red Dye
Photomicrograph showing positive Congo Red staining of the glassy pink material in the lamina propria from a duodenal biopsy confirming the amyloidosis type A deposition.
See this image and copyright information in PMC

References

    1. Amyloidosis. Introduction and overview. Kyle RA. J Intern Med. 1992;232:507–508. - PubMed
    1. Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience. Cowan AJ, Skinner M, Seldin DC, et al. Haematologica. 2013;98:141–146. - PMC - PubMed
    1. Hurlstone DP. J Gastroenterol Hepatol. Vol. 17. May: 2002. Iron-deficiency anemia complicating AL amyloidosis with recurrent small bowel pseudo-obstruction and hindgut sparing; pp. 623–622. - PubMed
    1. Gastrointestinal manifestations of amyloidosis. Ebert EC, Nagar M. Am J Gastroenterol. 2008;103:776–787. - PubMed
    1. Amyloidosis of the gastrointestinal tract and the liver: clinical context, diagnosis and management. Syed U, Ching Companioni RA, Alkhawam H, et al. http://journals.lww.com/eurojgh/Abstract/publishahead/Amyloidosis_of_the... Eur J Gastroenterol Hepatol. 2016:0. - PubMed

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