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Case Reports
. 2011 Nov 7:1:Doc06.
doi: 10.3205/oc000006. eCollection 2011.

Mucoepidermoid carcinoma of the bulbar conjunctiva - an interventional case report

Affiliations
Case Reports

Mucoepidermoid carcinoma of the bulbar conjunctiva - an interventional case report

Ana M Quintas et al. GMS Ophthalmol Cases. .

Abstract

Purpose: Mucoepidermoid carcinoma is a rare variant of squamous cell carcinoma of the conjunctiva. It appears more frequently in the elderly, it is more aggressive than squamous cell carcinoma, and it has a higher recurrence rate and higher incidence of intraocular and orbital invasion.

Methods: We report a case of a 74-year-old man who presented to the Emergency Department with a one month history of painful red left eye.

Results: The patient presented with visual acuity was 10/10 in both eyes and a conjunctiva tumor on the bulbar conjunctiva of left eye. The UBM revealed a thickening of the conjunctiva-sclera complex with no signs of intraocular invasion. A biopsy was performed and the diagnosis was of mucoepidermoid carcinoma. Two local excisions with adjuvant cryotherapy and mitomycin C aplication were carried out in a period of 6 months. After 9 months of follow-up there has not been any sign of recurrence.

Conclusions: The early diagnosis and treatment of carcinoma is essential not only to prevent the intraocular spread and preserve visual function but also to prevent local or systemic recurrence and dissemination.

Keywords: carcinoma; cryotherapy; mitomycin C; mucoepidermoid; treatment.

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Figures

Figure 1
Figure 1. Mucoepidermoid carcinoma of the bulbar conjunctiva before and after the treatment
Figure 2
Figure 2. Histopathology of mucoepidermoid carcinoma of conjuntiva. (a) Mucus-secreting cells highlighted by histochemical stain, mucicarmine, intermixed with squamous cells. (b) Immunohistochemistry stain, cytokeratin 14, highlights the invasive nature of the tumor.

References

    1. Saornil MA, Becerra E, Méndez MC, Blanco G. Tumores de la conjuntiva. [Conjunctival tumors]. Arch Soc Esp Oftalmol. 2009;84:7–22. doi: 10.4321/S0365-66912009000100003. Available from: http://dx.doi.org/10.4321/S0365-66912009000100003. - DOI - DOI - PubMed
    1. Robinson JW, Brownstein S, Jordan DR, Hodge WG. Conjunctival mucoepidermoid carcinoma in a patient with ocular cicatricial pemphigoid and a review of the literature. Surv Ophthalmol. 2006;51(5):513–519. doi: 10.1016/j.survophthal.2006.06.012. Available from: http://dx.doi.org/10.1016/j.survophthal.2006.06.012. - DOI - DOI - PubMed
    1. Panda A, Sharma N, Sen S, Ray M. Mucoepidermoid carcinoma of the conjunctiva managed by frozen section-guided excision and lamellar keratoplasty. Clin Experiment Ophthalmol. 2003;31(3):275–277. doi: 10.1046/j.1442-9071.2003.00653.x. Available from: http://dx.doi.org/10.1046/j.1442-9071.2003.00653.x. - DOI - DOI - PubMed
    1. Shields CL, Demirci H, Marr BP, Masheyekhi A, Materin M, Shields JA. Chemoreduction with topical mitomycin C prior to resection of extensive squamous cell carcinoma of the conjunctiva. Arch Ophthalmol. 2005;123(1):109–113. doi: 10.1001/archopht.123.1.109. Available from: http://dx.doi.org/10.1001/archopht.123.1.109. - DOI - DOI - PubMed
    1. Hwang IP, Jordan DR, Brownstein S, Gilberg SM, McEachren TM, Prokopetz R. Mucoepidermoid carcinoma of the conjunctiva: a series of three cases. Ophthalmology. 2000;107(4):801–805. doi: 10.1016/S0161-6420(99)00177-3. Available from: http://dx.doi.org/10.1016/S0161-6420(99)00177-3. - DOI - DOI - PubMed

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