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Case Reports
. 2014 Jan 8:4:Doc01.
doi: 10.3205/oc000014. eCollection 2014.

Bilateral panuveitis associated with Whipple disease - case report

Maria Lisboa  1 , Isabel Domingues  1 , Jaime Pamplona  2 , Pedro Barata  3 , Joana Morgado  4 , Vítor Brotas  5
Affiliations
Case Reports

Bilateral panuveitis associated with Whipple disease - case report

Maria Lisboa et al. GMS Ophthalmol Cases. .

Abstract

Purpose: To describe a clinical case and literature review of Whipple disease.

Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical work-up revealed a bilateral panuveitis and an ischemic cerebellar stroke.

Result: The diagnosis of Whipple disease was confirmed by histopathological analysis of adenopathy. The patient was treated with cortico-antibiotic therapy with significant clinical improvement.

Conclusion: Although rare, Whipple disease is potentially fatal if left untreated, it must be always be taken into consideration before any panuveitis of an unknown cause, even in the absence of gastrointestinal symptoms.

Keywords: Tropheryma Whippelli; Uveitis; Whipple.

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Figures

Figure 1
Figure 1. Figure 1 : Initial retinography and angiography (RE and LE)
Figure 2
Figure 2. Ganglionic biopsy, PAS
Figure 3
Figure 3. Retinography and angiography 2 months after the beginning of therapy (RE and LE)
Figure 4
Figure 4. Macular OCT of the right eye showing an epiretinal membrane
See this image and copyright information in PMC

References

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