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Comment
. 2016 Sep 14;20(3):280-282.
doi: 10.1016/j.chom.2016.08.011.

HIV Reservoir: Finding the Right Needles in a Needlestack

Alexander O Pasternak  1 , Ben Berkhout  2
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Free article
Comment

HIV Reservoir: Finding the Right Needles in a Needlestack

Alexander O Pasternak et al. Cell Host Microbe. .
Free article

Abstract

HIV forms a reservoir that persists despite prolonged therapy and is considered the main barrier to an HIV cure. Baxter et al. (2016) in this issue of Cell Host & Microbe and Boritz et al. (2016) in a recent Cell paper shed new light on HIV persistence in infected individuals.

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  • Multiple Origins of Virus Persistence during Natural Control of HIV Infection.
    Boritz EA, Darko S, Swaszek L, Wolf G, Wells D, Wu X, Henry AR, Laboune F, Hu J, Ambrozak D, Hughes MS, Hoh R, Casazza JP, Vostal A, Bunis D, Nganou-Makamdop K, Lee JS, Migueles SA, Koup RA, Connors M, Moir S, Schacker T, Maldarelli F, Hughes SH, Deeks SG, Douek DC. Boritz EA, et al. Cell. 2016 Aug 11;166(4):1004-1015. doi: 10.1016/j.cell.2016.06.039. Epub 2016 Jul 21. Cell. 2016. PMID: 27453467 Free PMC article.
  • Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.
    Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado GG, Routy JP, Walker BD, Finzi A, Chomont N, Kaufmann DE. Baxter AE, et al. Cell Host Microbe. 2016 Sep 14;20(3):368-380. doi: 10.1016/j.chom.2016.07.015. Epub 2016 Aug 18. Cell Host Microbe. 2016. PMID: 27545045 Free PMC article.

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