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Case Reports
. 2016 Sep;46(9):1096-9.
doi: 10.1111/imj.13181.

Cytomegalovirus-associated thrombocytopenia treated with thrombopoietin receptor agonist

J D Simpson  1 , G V Matthews  2   3 , T A Brighton  4 , J E Joseph  5
Affiliations
Case Reports

Cytomegalovirus-associated thrombocytopenia treated with thrombopoietin receptor agonist

J D Simpson et al. Intern Med J. 2016 Sep.

Abstract

Symptomatic cytomegalovirus (CMV) in immunocompetent individuals is an uncommon, yet recognised, phenomenon. This report discusses a case of CMV-associated thrombocytopenia refractory to immunomodulation and antivirals. Ultimately, a clinicopathological response was attained with eltrombopag. This is the first report of the efficacy of thrombopoietin receptor agonists in this context. This experience provides insight into possible pathogenic mechanisms of CMV-associated thrombocytopenia and presents a therapeutic option.

Keywords: cytomegalovirus; eltrombopag; immune thrombocytopenic purpura; platelets; treatment.

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