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Case Reports
. 2017 Feb;130(2):e51-e53.
doi: 10.1016/j.amjmed.2016.08.029. Epub 2016 Sep 13.

Out of Sight: Culture-Negative Endocarditis and Endophthalmitis

Caitlin Dugdale  1 , Sarah Brown  2 , Carine Davila  3 , Natalie Wolkow  4 , Gregory Fishbein  5 , Jennifer Sun  6 , Ebrahim Barkoudah  2 , Holly Rawizza  7
Affiliations
Case Reports

Out of Sight: Culture-Negative Endocarditis and Endophthalmitis

Caitlin Dugdale et al. Am J Med. 2017 Feb.
No abstract available

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Color photomicrograph with hazy view of the left retina due to significant vitritis.
Figure 2
Figure 2
A) Histologic section of the aortic valve and vegetation demonstrating healing endocarditis with granulation tissue, fibrin deposition (arrows), and calcified debris admixed with acute inflammatory cells in the absence of identifiable microorganisms or foamy macrophages. (H&E, 40×). B) Periodic acid-Schiff (PAS) stain with diastase fails to demonstrate PAS-positive organisms within macrophages (400×).
See this image and copyright information in PMC

References

    1. Whipple GH. A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues. Johns Hopkins Hospital Bulletin. 1907
    1. Fenollar F, Puechal X, Raoult D. Medical progress - Whipple's disease. New England Journal of Medicine. 2007;356:55–66. - PubMed
    1. Fenollar F, Trani M, Davoust B, et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. The Journal of infectious diseases. 2008;197:880–887. - PubMed
    1. Schoniger-Hekele M, Petermann D, Weber B, Muller C. Tropheryma whipplei in the environment: survey of sewage plant influxes and sewage plant workers. Appl Environ Microbiol. 2007;73:2033–2035. - PMC - PubMed
    1. Geissdorfer W, Moos V, Moter A, et al. High frequency of Tropheryma whipplei in culture-negative endocarditis. Journal of clinical microbiology. 2012;50:216–222. - PMC - PubMed

Publication types