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. 2016 Dec;74(4):537-544.
doi: 10.1007/s12013-016-0762-5. Epub 2016 Sep 16.

Electrooptical Analysis of Microbial Cell Suspensions forDetermination of Antibiotic Resistance

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Electrooptical Analysis of Microbial Cell Suspensions forDetermination of Antibiotic Resistance

Olga I Guliy et al. Cell Biochem Biophys. 2016 Dec.

Abstract

The effects of ampicillin; kanamycin, chloramphenicol, and tetracycline on electrophysical characteristics of cells of sensitive (ampicillin; kanamycin, chloramphenicol) and resistant (ampicillin; kanamycin, chloramphenicol, tetracycline) Escherichia coli strains were studied. Under the action of antibiotics sensitive and resistant E. coli strains acquire different electro-optical properties. Changes in suspension-orientational spectra, that are observed under the action of ampicillin; kanamycin, chloramphenicol, and tetracycline can be used in determination of antibiotic resistance of the studied bacterial strains. In our opinion, the methods of microbial suspension electro-optical analysis can be used in microbiology, mеdicinе, veterinary, and are an effective tool for solving the problems connected with determination of microbial cell antibiotic resistance.

Keywords: Ampicillin; Cells orientational spectrum; Chloramphenicol; Escherichia coli; Kanamycin; Tetracycline.

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