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Editorial
. 2017 Feb;17(2):318-319.
doi: 10.1111/ajt.14051. Epub 2016 Oct 12.

Validation Is Critical for Genome-Wide Association Study-Based Associations

Affiliations
Editorial

Validation Is Critical for Genome-Wide Association Study-Based Associations

W S Oetting et al. Am J Transplant. 2017 Feb.
No abstract available

Keywords: editorial/personal viewpoint; genetics; genomics; kidney transplantation/nephrology; microarray/gene array; molecular biology; molecular biology: single polynucleotide polymorphism; statistics.

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Conflict of interest statement

The authors of this manuscript have no conflicts of interest to disclose as described by the American Journal of Transplantation.

Comment on

References

    1. Zöllner S, Pritchard JK. Overcoming the winner’s curse: Estimating penetrance parameters from case-control data. Am J Hum Genet. 2007;80:605–615. - PMC - PubMed
    1. Philstrøm H, Mjøen G, Mucha S, et al. Single nucleotide polymorphisms and long term clinical outcome in renal transplant patients. A validation study. Am J Transplant. 2016 IN PRESS-THIS ISSUE. - PubMed
    1. O'Brien RP, Phelan PJ, Conroy J, et al. A genome-wide association study of recipient genotype and medium-term kidney allograft function. Clin Transplant. 2013;27:379–387. - PubMed
    1. Pashler H, Harris CR. Is the replicability crisis overblown? Three arguments examined. Persp Psychol Sci. 2012;7:531–536. - PubMed
    1. International Genetics & Translational Research in Transplantation Network (iGeneTRAiN) Design and implementation of the International Genetics & Translational Research in Transplantation Network (iGeneTRAiN) Transplant. 2015;99:2401–2412. - PMC - PubMed