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Review
. 2016 May 13:24:64.
doi: 10.11604/pamj.2016.24.64.6291. eCollection 2016.

Isolated localization of Rosai Dorfman disease as renal mass: a case report and review of literature

Aziz El Majdoub  1 , Aziza El Houari  2 , Laila Chbani  2 , Hinde El Fatemi  2 , Abdelhak Khallouk  1 , Moulay Hassan Farih  1
Affiliations
Review

Isolated localization of Rosai Dorfman disease as renal mass: a case report and review of literature

Aziz El Majdoub et al. Pan Afr Med J. .

Abstract

We report a rare case of an elderly woman presented with right renal mass with invasion of renal vein and several small lymphadenopathy in the hilar area. The diagnosis of kidney cancer is suspected and the patient underwent open radical nephrectomy, surrenalectomy and lymphadenectomy dissection. The pathologic examinations find a rosai dorfman disease. This unusual benign entity is uncommon in the kidney, but in medical imaging, it may simulate an infiltrative renal neoplasm, especially a lymphoma or leukemia or even renal cell carcinoma. A comprehensive literature review was undertaken to summarize the clinical and pathologic features of this disorder.

Keywords: Rosai dorfman disease; emperipolesis; extranodal; renal mass.

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Figures

Figure 1
Figure 1
Abdominal and pelvic computed tomography scan showed the presence of a large tissue process at the upper pole of the right kidney measuring 8 cm of diameter, demonstrating heterogeneous contrast enhancement
Figure 2
Figure 2
Abdominal and pelvic computed tomography scan showed that the process extends over the hilar area with invasion of the right renal vein, while the lower vena cava is permeable
Figure 3
Figure 3
Abdominal Computed tomography scan showed Several small lymphadenopathy in the right hilar area
Figure 4
Figure 4
High-power magnification demonstrating histiocytic proliferation with intracytoplasmic lymphocytes (emperipolesis, arrows), Hematoxylin-eosin stain, original magnification x40
Figure 5
Figure 5
High-power magnification with cytoplasmic immunostaining of histiocytic marker (CD68) highlighting proliferating cells (CD68 stain, original magnification x40)
See this image and copyright information in PMC

References

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