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Case Reports
. 2016 Aug 15:19:98-102.
doi: 10.1016/j.rmcr.2016.08.003. eCollection 2016.

Life threatening hemoptysis from Hughes Stovin syndrome: Is it that rare?

Mohammed Abdelbary  1 , Ahmed El-Masry  2 , Motaz S Rabie  3
Affiliations
Case Reports

Life threatening hemoptysis from Hughes Stovin syndrome: Is it that rare?

Mohammed Abdelbary et al. Respir Med Case Rep. .

Abstract

Introduction: Hughes-Stovin syndrome is a life-threatening disorder of unknown etiology. This condition is characterized by vasculitis, deep venous thrombosis and aneurysms that mainly involve the pulmonary arteries resulting in hemoptysis. It has been described in literature less than 40 times. However, we believe it is not very uncommon as it might be diagnosed as pulmonary embolism solely. In such cases, anticoagulation therapy augments the risk of life-threatening hemoptysis.

Materials and methods: We report the case of a 35 years old, Egyptian female patient with Hughes-Stovin syndrome, who initially presented with lower limb deep vein thrombosis and coughing of blood. Anticoagulation regimen for pulmonary embolism was given. This resulted in massive hemoptysis that was successfully controlled by medical therapy.

Conclusion: Adults who present with venous thrombosis and hemoptoic cough, with no predisposing factors of thrombosis, normal platelet count and coagulation, the possibility of Hughes-Stovin syndrome has to be considered.

Keywords: Deep venous thrombosis; Hemoptysis; Pulmonary aneurysm; Pulmonary embolism; Thrombophlebitis.

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Figures

Fig. 1
Fig. 1
CT angiography of the pulmonary arteries (a) Axial view (b) Coronal view showing right main pulmonary artery aneurysm with circumferential thrombotic filling defect (Thin arrows) and ectatic adjacent bronchial arteries (Thick arrows).
Fig. 2
Fig. 2
CT angiography of the pulmonary arteries (a) Axial view (b) Coronal view showing left lower lobe pulmonary artery aneurysm with mural thrombotic filling defect (Thin arrows).
Fig. 3
Fig. 3
Catheter angiography of the pulmonary arteries(a) Right pulmonary artery aneurysm (thick arrow) with lower lobe perfusion defect (curved arrow) (b) Left segmental pulmonary artery aneurysm (thick arrow).
See this image and copyright information in PMC

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