Mediating signaling response to actin-mediated forces: Cas-L is causal in the T-cell response to forces triggered by antigen presentation

Ye Chen^{1

2}, Sarah M Russell^{1

2

3

4}

Affiliations

¹ Immune Signalling Laboratory, Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
² Centre for Micro-Photonics, School of Science, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria, Australia.
³ Department of Pathology, The University of Melbourne, Victoria, Australia.
⁴ Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia.

Comment

Ye Chen et al. Immunol Cell Biol. 2016 Nov.

. 2016 Nov;94(10):905-906.

doi: 10.1038/icb.2016.79. Epub 2016 Sep 20.

Ye Chen^{1

2}, Sarah M Russell^{1

2

3

4}

¹ Immune Signalling Laboratory, Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
² Centre for Micro-Photonics, School of Science, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria, Australia.
³ Department of Pathology, The University of Melbourne, Victoria, Australia.
⁴ Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia.

No abstract available

Comment on

Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability.
Santos LC, Blair DA, Kumari S, Cammer M, Iskratsch T, Herbin O, Alexandropoulos K, Dustin ML, Sheetz MP. Santos LC, et al. Immunol Cell Biol. 2016 Nov;94(10):981-993. doi: 10.1038/icb.2016.61. Epub 2016 Jun 30. Immunol Cell Biol. 2016. PMID: 27359298 Free PMC article.