Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Jun 1;260(2):601-4.
doi: 10.1042/bj2600601.

The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region

M Leyh-Bouille  1 , J Van Beeumen, S Renier-Pirlot, B Joris, M Nguyen-Distèche, J M Ghuysen
Affiliations

The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region

M Leyh-Bouille et al. Biochem J. .

Abstract

The N-terminal region of the Streptomyces K15 DD-peptidase/penicillin-binding protein shows high homology with that of other penicillin-interactive proteins or domains. The active-site serine residue of the conserved tetrad Ser-Xaa-Xaa-Lys occurs at position 35. There is no indication for the presence of a signal peptide or an N-terminal hydrophobic sequence, suggesting that the Streptomyces K15 enzyme is probably anchored to the membrane by a C-terminal peptide segment.

PubMed Disclaimer

References

    1. Biochem J. 1986 Apr 1;235(1):167-76 - PubMed
    1. J Bacteriol. 1986 Jul;167(1):257-64 - PubMed
    1. Eur J Biochem. 1986 Oct 15;160(2):231-8 - PubMed
    1. EMBO J. 1986 Sep;5(9):2399-405 - PubMed
    1. Eur J Biochem. 1987 Feb 2;162(3):509-18 - PubMed

Publication types