Why internal weights should be avoided (not only) in MR-Egger regression

Fernando Pires Hartwig^{1

2}, Neil Martin Davies^{2

3}

Affiliations

¹ Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil fernandophartwig@gmail.com.
² Medical Research Council Integrative Epidemiology Unit and.
³ School of Social and Community Medicine, University of Bristol, Bristol, UK.

Comment

Fernando Pires Hartwig et al. Int J Epidemiol. 2016 Oct.

. 2016 Oct;45(5):1676-1678.

doi: 10.1093/ije/dyw240. Epub 2016 Sep 20.

Fernando Pires Hartwig^{1

2}, Neil Martin Davies^{2

3}

¹ Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil fernandophartwig@gmail.com.
² Medical Research Council Integrative Epidemiology Unit and.
³ School of Social and Community Medicine, University of Bristol, Bristol, UK.

No abstract available

Comment in

Response to Hartwig and Davies.
Bowden J, Burgess S, Davey Smith G. Bowden J, et al. Int J Epidemiol. 2016 Oct;45(5):1679-1680. doi: 10.1093/ije/dyw252. Epub 2016 Sep 20. Int J Epidemiol. 2016. PMID: 27649802 Free PMC article. No abstract available.
Authors' response to Hartwig and Davies.
Kemp FJ, Sayers A, Davey Smith G, Tobias JH, Evans DM. Kemp FJ, et al. Int J Epidemiol. 2016 Oct;45(5):1678-1679. doi: 10.1093/ije/dyw241. Epub 2016 Sep 20. Int J Epidemiol. 2016. PMID: 27649804 Free PMC article. No abstract available.

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression.
Bowden J, Davey Smith G, Burgess S. Bowden J, et al. Int J Epidemiol. 2015 Apr;44(2):512-25. doi: 10.1093/ije/dyv080. Epub 2015 Jun 6. Int J Epidemiol. 2015. PMID: 26050253 Free PMC article.
Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children.
Kemp JP, Sayers A, Smith GD, Tobias JH, Evans DM. Kemp JP, et al. Int J Epidemiol. 2016 Oct;45(5):1560-1572. doi: 10.1093/ije/dyw079. Epub 2016 May 22. Int J Epidemiol. 2016. PMID: 27215616 Free PMC article.