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. 2017 Aug;17(3):411-414.
doi: 10.1007/s10238-016-0437-y. Epub 2016 Sep 20.

CXCL4 in undifferentiated connective tissue disease at risk for systemic sclerosis (SSc) (previously referred to as very early SSc)

Gabriele Valentini  1   2   3 , Antonella Riccardi  4   5   6 , Serena Vettori  4   5   6 , Rosaria Irace  4   5   6 , Michele Iudici  4   5   6 , Salvatore Tolone  4   5   6 , Ludovico Docimo  4   5   6 , Marialuisa Bocchino  4   5   6 , Alessandro Sanduzzi  4   5   6 , Domenico Cozzolino  4   5   6
Affiliations

CXCL4 in undifferentiated connective tissue disease at risk for systemic sclerosis (SSc) (previously referred to as very early SSc)

Gabriele Valentini et al. Clin Exp Med. 2017 Aug.

Abstract

The aim of the study was to evaluate CXCL4 levels in undifferentiated connective tissue disease at risk for SSc (UCTD-SSc-risk) and confirm its increase and investigate its prognostic value. Serum CXCL4 levels were measured in 45 patients and 24 controls. CXCL4 was significantly higher in UCTD-SSc-risk patients than in controls. It resulted higher in patients with a shorter disease duration and in those lacking capillaroscopic alterations. We confirm that CXCL4 levels are increased in UCTD-risk-SSc patients. Further studies are needed to investigate the role of CXCL4 assessment in UCTD-risk-SSc.

Keywords: Systemic sclerosis; Undifferentiated connective tissue disease.

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References

    1. Arthritis Rheum. 2013 Nov;65(11):2737-47 - PubMed
    1. Arthritis Res Ther. 2013;15(3):R63 - PubMed
    1. Arthritis Care Res (Hoboken). 2014 Oct;66(10):1520-7 - PubMed
    1. Autoimmun Rev. 2015 Mar;14(3):210-3 - PubMed
    1. Arthritis Rheum. 2000 Feb;43(2):444-51 - PubMed

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