Zika virus-associated brain damage: animal models and open issues

Affiliations

¹ Faculty of Veterinary Medicine, University of Teramo, Località Piano d'Accio, Teramo 64100, Italy.
² Department of Surgery, Stem Cell Laboratory, University of São Paulo, Saint Paul 05508-270, Brazil.
³ Department of Immunology, Neuroimmune Interactions Laboratory, University of São Paulo, Saint Paul 05508-000, Brazil.

Giovanni Di Guardo et al. Emerg Microbes Infect. 2016.

. 2016 Sep 21;5(9):e106.

doi: 10.1038/emi.2016.103.

¹ Faculty of Veterinary Medicine, University of Teramo, Località Piano d'Accio, Teramo 64100, Italy.
² Department of Surgery, Stem Cell Laboratory, University of São Paulo, Saint Paul 05508-270, Brazil.
³ Department of Immunology, Neuroimmune Interactions Laboratory, University of São Paulo, Saint Paul 05508-000, Brazil.

No abstract available

References

1. Fauci AS, Morens DM. Zika virus in the Americas–yet another arbovirus threat. N Engl J Med 2016; 374: 601–604. - PubMed
1. Paixão ES, Barreto F, Teixeira MdaG, Costa MdaC, Rodrigues LC. History, epidemiology, and clinical manifestations of Zika: a systematic review. Am J Public Health 2016; 106: 606–612. - PMC - PubMed
1. Brazilian Ministry of Health. Centro de Operações de Emergências em Saúde Pública sobre Microcefalias (COES–Microcefalias), Informe Epidemiológico nº 32, Semana Epidemiológica (SE) 25/2016 (19/06 a 25/06/2016), Monitoramento dos Casos de Microcefalia no Brasil, 25 June 2016. Available at http://combateaedes.saude.gov.br/en/epidemiological-situation#epidemiolo... (accessed on 14 July 2016).
1. Check Hayden E. Proving Zika link to birth defects poses huge challenge. Nature 2016; 530: 142–143. - PubMed
1. Li C, Xu D, Ye Q et al. Zika virus disrupts neural progenitor development and leads to microcephaly in mice. Stem Cell 2016; 19: 120–126. - PubMed