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. 2016 Sep 1;17(3):150-4.
doi: 10.5152/jtgga.2016.16073. eCollection 2016.

The effect of adenomyosis on the outcomes of laparoscopic hysterectomy

Ali Yavuzcan  1 , Alper Başbuğ  1 , Merve Baştan  1 , Mete Çağlar  1 , İsmail Özdemir  1
Affiliations

The effect of adenomyosis on the outcomes of laparoscopic hysterectomy

Ali Yavuzcan et al. J Turk Ger Gynecol Assoc. .

Abstract

Objective: The presence of adenomyosis (ADS) may increase complication rates associated with laparoscopic hysterectomy (LH) due to an increased weight of the uterus, increased vascularization of the uterus, impaired myometrial tissue, and presence of additional gynecological pathologies such as leiomyoma or endometriosis. The aim of the present study was to evaluate perioperative and early postoperative parameters in patients with or without adenomyotic lesions.

Material and methods: The study included patients who underwent LH in a university hospital. Patient data were retrieved from the hospital records and reviewed retrospectively. Sixty-one patients (85.9%) without adenomyotic lesions comprised the control group. Ten patients with adenomyotic lesions (14.1%) were regarded as the study group.

Results: In this study, the mean age of the patients was 50.93±9.39 years. The mean uterus size was significantly higher in patients with ADS (p=0.02). There was no statistically significant difference in perioperative variables such as delta hemoglobin (Hb), insertion of pelvic drainage catheter, and invasive assessment of the urinary tract between both the groups (p=0.27, p=1.0, and p=0.67, respectively). The difference between the groups in terms of postoperative blood transfusion was not statistically significant (p=0.25). There was no statistically significant difference in the postoperative maximum body temperature, length of hospital stay, and duration of urinary catheterization between both the groups (p=0.77, p=0.36, and p=0.75, respectively).

Conclusion: LH appears to be a safe alternative for patients with ADS. Large-scale, prospective, and randomized trials are required in order to suggest the routine use of LH in patients preoperatively diagnosed with ADS.

Keywords: Adenomyosis; laparoscopic hysterectomy; outcomes.

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References

    1. Ferenczy A. Pathophysiology of Adenomyosis. Hum Reprod Update. 1998;4:312–22. http://dx.doi.org/10.1093/humupd/4.4.312. - DOI - PubMed
    1. Parazzini F, Mais V, Cipriani S, Busacca M, Venturini P GISE. Determinants of Adenomyosis in women who underwent hysterectomy for benign gynecological conditions: results from a prospective multicentric study in Italy. Eur J Obstet Gynecol Reprod Biol. 2009;143:103–6. http://dx.doi.org/10.1016/j.ejogrb.2008.12.010. - DOI - PubMed
    1. Li T, Li YG, Pu DM. Matrix metalloproteinase-2 and -9 expression correlated with angiogenesis in human Adenomyosis. Gynecol Obstet Invest. 2006;62:229–35. http://dx.doi.org/10.1159/000094426. - DOI - PubMed
    1. Goteri G, Lucarini G, Montik N, Zizzi A, Stramazzotti D, Fabris G, et al. Expression of vascular endothelial growth factor (VEGF), hypoxia inducible factor-1 alpha (HIF-1 alpha), and microvessel density in endometrial tissue in women with adenomyosis. Int J Gynecol Pathol. 2009;28:157–63. http://dx.doi.org/10.1097/PGP.0b013e318182c2be. - DOI - PubMed
    1. Pepas L, Deguara C, Davis C. Update on the surgical management of Adenomyosis. Curr Opin Obstet Gynecol. 2012;24:259–64. http://dx.doi.org/10.1097/GCO.0b013e328355213a. - DOI - PubMed

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