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. 2016:2016:7297092.
doi: 10.1155/2016/7297092. Epub 2016 Aug 29.

Evaluating Bone Health in Egyptian Children with Forearm Fractures: A Case Control Study

Abeer El-Sakka  1 , Cristina Penon  2 , Adham Hegazy  1 , Salwa Elbatrawy  3 , Amr Gobashy  1 , Alvaro Moreira  2
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Evaluating Bone Health in Egyptian Children with Forearm Fractures: A Case Control Study

Abeer El-Sakka et al. Int J Pediatr. 2016.

Abstract

Objective. To determine the likelihood of vitamin D deficiency and low bone mineral density in Egyptian children with forearm fractures. Methods. A case control study of 46 children aged 3 to 10 years with or without forearm fractures. Validated questionnaires were used to assess calcium and vitamin D intake as well as sun exposure. Serum calcium, phosphorus, alkaline phosphatase, and 25-hydroxy-vitamin D were collected. Bone mineral density was evaluated using dual-energy X-ray absorptiometry. Results. Compared to the Control group, calcium and vitamin D intake was lower in the Cases group (p = 0.03). Cases had higher Body Mass Index than Controls, p = 0.01. Children in the Cases group had lower mean serum calcium values 8.3 ± 1.4 compared to 9.3 ± 1.1 in Controls (p = 0.01). Alkaline phosphatase was higher in Cases 265 ± 65.8 than Controls 226 ± 54.6 (p = 0.03). Vitamin D and bone mineral density scores were significantly lower in the Cases group (p < 0.05). Conclusion. Our data shows an increased rate of vitamin D deficiency and decreased bone mineral density in Egyptian children with forearm fractures.

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Figures

Figure 1
Figure 1
Bone mineral density in Cases and Controls. ∗ signifies p value ≤ 0.05.
Figure 2
Figure 2
Serum calcium correlation to vitamin D. ∗ R 2 = 0.334, p < 0.01.
See this image and copyright information in PMC

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