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Comment
. 2016 Sep 20;45(3):468-470.
doi: 10.1016/j.immuni.2016.09.006.

Homegrown Macrophages

Ki-Wook Kim  1 , Nan Zhang  1 , Kyunghee Choi  1 , Gwendalyn J Randolph  2
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Free article
Comment

Homegrown Macrophages

Ki-Wook Kim et al. Immunity. .
Free article

Abstract

Macrophages residing in different organs have diverse gene-expression programs. Mass et al. (2016) propose that this diversity develops "at home"-within those organs-after the recruitment of a common precursor that had not made prior commitments to diversity.

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  • Specification of tissue-resident macrophages during organogenesis.
    Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F. Mass E, et al. Science. 2016 Sep 9;353(6304):aaf4238. doi: 10.1126/science.aaf4238. Epub 2016 Aug 4. Science. 2016. PMID: 27492475 Free PMC article.