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Review
. 2017 Mar;57(3):287-296.
doi: 10.1002/jcph.830. Epub 2016 Nov 4.

Reinventing HCV Treatment: Past and Future Perspectives

Wendy Carter  1 , Sarah Connelly  1 , Kimberly Struble  1
Affiliations
Review

Reinventing HCV Treatment: Past and Future Perspectives

Wendy Carter et al. J Clin Pharmacol. 2017 Mar.

Abstract

This review paper summarizes the epidemiology of hepatitis C virus (HCV) and chronic HCV infection, including HCV virology and treatment regimens. Specifically, we focus on the evolution of past, current, and future HCV treatment options, the reasons for treatment failure, and the impact of resistance-associated variants on treatment success.

Keywords: direct-acting antivirals; genotype; hepatitis C; resistance-associated variants; sustained virologic response.

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