Review
doi: 10.1002/jcph.830.
Epub 2016 Nov 4.
Reinventing HCV Treatment: Past and Future Perspectives
Affiliations
- PMID: 27654843
- DOI: 10.1002/jcph.830
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Review
Reinventing HCV Treatment: Past and Future Perspectives
J Clin Pharmacol.
2017 Mar.
Abstract
This review paper summarizes the epidemiology of hepatitis C virus (HCV) and chronic HCV infection, including HCV virology and treatment regimens. Specifically, we focus on the evolution of past, current, and future HCV treatment options, the reasons for treatment failure, and the impact of resistance-associated variants on treatment success.
Keywords: direct-acting antivirals; genotype; hepatitis C; resistance-associated variants; sustained virologic response.
© 2016, The American College of Clinical Pharmacology.
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