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Editorial
. 2016 Aug;5(4):420-3.
doi: 10.21037/tlcr.2016.08.06.

Pros: Can tissue biopsy be replaced by liquid biopsy?

Marius Ilié  1 , Paul Hofman  1
Affiliations
Editorial

Pros: Can tissue biopsy be replaced by liquid biopsy?

Marius Ilié et al. Transl Lung Cancer Res. 2016 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: P Hofman declares receiving honoraria from pharmaceutical (AstraZeneca, Roche, Novartis, Bristol Myers Squibb) and biotechnology (Qiagen, Janssen, Biocartis) companies for attendance at advisory board meetings. M Ilié has no conflicts of interest to declare.

Comment in

  • Rebuttal from Dr. Mino-Kenudson.
    Mino-Kenudson M. Mino-Kenudson M. Transl Lung Cancer Res. 2016 Aug;5(4):430-2. doi: 10.21037/tlcr.2016.08.02. Transl Lung Cancer Res. 2016. PMID: 27657667 Free PMC article. No abstract available.
  • Commentary on tumor heterogeneity.
    Popper HH. Popper HH. Transl Lung Cancer Res. 2016 Aug;5(4):433-5. doi: 10.21037/tlcr.2016.08.07. Transl Lung Cancer Res. 2016. PMID: 27659489 Free PMC article. No abstract available.

References

    1. Gerlinger M, Rowan AJ, Horswell S, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012;366:883-92. 10.1056/NEJMoa1113205 - DOI - PMC - PubMed
    1. Bedard PL, Hansen AR, Ratain MJ, et al. Tumour heterogeneity in the clinic. Nature 2013;501:355-64. 10.1038/nature12627 - DOI - PMC - PubMed
    1. Sholl LM, Aisner DL, Allen TC, et al. Liquid Biopsy in Lung Cancer: A Perspective From Members of the Pulmonary Pathology Society. Arch Pathol Lab Med 2016;140:825-9. 10.5858/arpa.2016-0163-SA - DOI - PubMed
    1. Wong SQ, Li J, Tan AY, et al. Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing. BMC Med Genomics 2014;7:23. 10.1186/1755-8794-7-23 - DOI - PMC - PubMed
    1. Ilie M, Hofman V, Long E, et al. Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine? Ann Transl Med 2014;2:107. - PMC - PubMed

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