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Case Reports
. 2016 Aug;10(8):ZD38-40.
doi: 10.7860/JCDR/2016/20013.8362. Epub 2016 Aug 1.

Desmoplastic Ameloblastoma Arising in a Dentigerous Cyst - A Case Report and Discussion

Muruganandhan Jayanandan  1 , Shaik Mohamed Shamsudeen  2 , Satish Kumar Srinivasan  2 , S Nalin Kumar  3 , Tyson Babu Pulikkottil  4
Affiliations
Case Reports

Desmoplastic Ameloblastoma Arising in a Dentigerous Cyst - A Case Report and Discussion

Muruganandhan Jayanandan et al. J Clin Diagn Res. 2016 Aug.

Abstract

Dentigerous cyst is a fairly common odontogenic cyst with an uncomplicated prognosis. However, reports of odontogenic and non-odontogenic tumors arising from the cysts have been published for many years. Therefore, the importance of thorough histopathological examination and regular follow-up cannot be overemphasized. Here is a case report of a possible development of desmoplastic ameloblastoma from a dentigerous cyst. This case is unique for two main reasons. Firstly, to our knowledge such a case has not been reported previously. Secondly, the tumor seemed to arise from the capsule and not from lining of the dentigerous cyst. Transformation of odontogenic rests into cysts is known to occur in the syndromic cases of odontogenic keratocysts (resulting in recurrent and daughter cysts) but not in dentigerous cysts. This case report may prompt greater interest in the role of the supposedly inactive odontogenic nests in the capsule of these cysts.

Keywords: Cyst-tumor transformation; Desmoplasia; Odontogenic cyst; Odontogenic tumor.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Orthopantomograph of the patient showing radiolucency around the crown of impacted 45.
[Table/Fig-2]:
[Table/Fig-2]:
Post-surgical photograph.
[Table/Fig-3]:
[Table/Fig-3]:
Gross specimen before processing.
[Table/Fig-4]:
[Table/Fig-4]:
Photomicrograph showing the cyst lining and capsule – hematoxylin and eosin, 10X magnification.
[Table/Fig-5a,b]:
[Table/Fig-5a,b]:
Photomicrograph showing the odontogenic nests – hematoxylin and eosin, 4X and 10X magnification respectively.
[Table/Fig-6a,b]:
[Table/Fig-6a,b]:
Photomicrograph showing the desmoplastic focus – hematoxylin and eosin, 4X and 10X magnification respectively.
[Table/Fig-7]:
[Table/Fig-7]:
Photomicrograph showing the ameloblastic cells – hematoxylin and eosin, 40X magnification.
[Table/Fig-8a,b]:
[Table/Fig-8a,b]:
Photomicrograph showing the stromal induction of the epithelial cells – Hematoxylin and eosin, 40X magnification.
[Table/Fig-9]:
[Table/Fig-9]:
Photomicrograph showing osseous metaplasia – hematoxylin and eosin, 10X magnification.
[Table/Fig-10]:
[Table/Fig-10]:
Six month follow-up OPG.
See this image and copyright information in PMC

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