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Editorial
. 2017 Jan 2;16(1):7-8.
doi: 10.1080/15384101.2016.1232085. Epub 2016 Sep 22.

Dynein: Let's not get stuck!

Affiliations
Editorial

Dynein: Let's not get stuck!

Babu J N Reddy et al. Cell Cycle. .
No abstract available

Keywords: Lis1 molecular motor; NudE; cargo transport; dynein; in vivo force production; lipid droplet.

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Figures

Figure 1.
Figure 1.
Cartoon of a lipid droplet in the optical trap. Lower: dark circle: lipid droplet; red parabolic lines: optical trap, exerting a centripetal force (red arrow) on the droplet when displaced from trap center. Horizontal black lines: dynein motors, attached to microtubule (blue). Upper: enlargement of the lower portion of the lipid droplet, showing attached dynein motors in black, with NudE (red) and Lis1 (green) cofactors. Two dyneins on left: pre-adaptation stage, with un-extended NudE (red, short) and Lis1 (green) that is not interacting with the dynein motor domains (ovals). Five dyneins on right: adapted dynein; NudE extended, Lis1 interacting with the dynein motor domains.

Comment on

References

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